1. Tomohiko Sato - Home
Tomohiko Sato · Most frequent co-Author · Most cited colleague · Most frequent Affiliation.
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2. Tomohiko Sato - DNMT3A R882 mutants interact with polycomb ...
Molecularly, the DNMT3A mutant interacts with polycomb repressive complex 1 (PRC1), causing transcriptional silencing, revealing a DNA methylation-independent ...
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3. Silent-Iconic, form and function come together - Fuorisalone.it
30 aug 2021 · We talked about it with Tomohiko Sato, Senior Designer Product Design Department at Hitachi Cooling & Heating. Introduce yourselves: who are ...
Silent-Iconic, the new panel for 4-way cassettes produced by Hitachi Cooling & Heating, designed to integrate technological performance with meticulous design. Available in white and an exclusive black version, it responds to various applications, from commercial to residential air conditioning. We talked about it with Tomohiko Sato, Senior Designer Product Design Department at Hitachi Cooling & Heating.
4. Incidence and severity of adverse effects related to platelet transfusion
Correspondence to: Tomohiko Sato. Department of Transfusion Medicine and ... revealed that the short shelf-life of PC is associated with a low TTBI ...
Incidence and severity of adverse effects related to platelet transfusion: a narrative review of the literature and the recent hemovigilance data of Japan
5. Metagenomic Thermometer | DNA Research - Oxford Academic
Tomohiko Sato ,. Tomohiko Sato. Earth-Life Science Institute, Tokyo Institute ... revealed that OGT of prokaryotes can be accurately predicted based on ...
See AlsoMinn Kota PawsAbstract. Various microorganisms exist in environments, and each of them has its optimal growth temperature (OGT). The relationship between genomic informa
6. DNMT3A R882 mutants interact with polycomb proteins to block ...
Junji Koya, Keisuke Kataoka, Tomohiko Sato ... Molecularly, the DNMT3A mutant interacts with polycomb repressive complex 1 (PRC1), causing transcriptional ...
Despite the clinical impact of DNMT3A mutation on acute myeloid leukaemia, the molecular mechanisms regarding how this mutation causes leukaemogenesis in vivo are largely unknown. Here we show that, in murine transplantation experiments, recipients transplanted with DNMT3A mutant-transduced cells exhibit aberrant haematopoietic stem cell (HSC) accumulation. Differentiation-associated genes are downregulated without accompanying changes in methylation status of their promoter-associated CpG islands in DNMT3A mutant-transduced stem/progenitor cells, representing a DNA methylation-independent role of mutated DNMT3A. DNMT3A R882H also promotes monoblastic transformation in vitro in combination with HOXA9. Molecularly, the DNMT3A mutant interacts with polycomb repressive complex 1 (PRC1), causing transcriptional silencing, revealing a DNA methylation-independent role of DNMT3A mutation. Suppression of PRC1 impairs aberrant HSC accumulation and monoblastic transformation. From our data, it is shown that DNMT3A mutants can block the differentiation of HSCs and leukaemic cells via PRC1. This interaction could be targetable in DNMT3A-mutated leukaemias.
7. Mass spectrometry imaging reveals differential localization of ... - Nature
20 jan 2020 · ... reveals differential localization of natural sunscreens in the mantle of the giant clam Tridacna crocea. Naoko Goto-Inoue,; Tomohiko Sato, ...
Giant clams have evolved to maximize sunlight utilization by their photosymbiotic partners, while affording them protection from harmful ultraviolet (UV) light. The presence of UV absorbing substances in the mantle is thought to be critical for light protection; however, the exact localization of such compounds remains unknown. Here, we applied a combination of UV liquid chromatography (LC), LC-mass spectrometry (MS), MS imaging, and UV micrography to localize UV absorbing substances in the giant clam Tridacna crocea. LC-MS analysis revealed that the animal contained three classes of mycosporines: progenitor, primary, and secondary mycosporines. MS imaging revealed that primary and secondary mycosporines were localized in the outermost layer of the mantle; whereas progenitor mycosporines were distributed throughout the mantle tissue. These findings were consistent with the results of UV micrography, which revealed that the surface layer of the mantle absorbed UV light at 320 ± 10 nm. This is the first report indicating that progenitor and primary mycosporines are metabolized to secondary mycosporines by the giant clam and that they are differentially localized in the surface layer of the mantle to protect the animal from UV light.
8. Inter Research » AB » v25 » p97-106
24 aug 2016 · Naoyuki Miyata1,*, Tomohiko Mori1, Masaaki Kagehira2, Nobuyuki ... Sato K (2016) Micro CTD data logger reveals short-term excursions of ...
Naoyuki Miyata1,*, Tomohiko Mori1, Masaaki Kagehira2, Nobuyuki Miyazaki3, Michihiko Suzuki4, Katsufumi Sato1
9. Details of a Researcher - SATO Yusuke
FUJITA Hiromu, MOTOYAMA Satoru, SASAKI Tomohiko, SATO Yusuke, KAWAKITA Yuta, NAKAMURA Masakatsu. Nihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical ...
Extensive lymph node dissection around the left laryngeal nerve achieved with robot-assisted thoracoscopic esophagectomy
10. Tomohiko ITO - Anime News Network
SAO Director Tomohiko Ito Reveals Hello World Film's Cast, Story, September ... Sato (The 10... news. 18 comments. My Hero Academia Anime Gets 'Final ...